The Drastic Quad RS-422 adapter is designed for a 1x PCIe slot. This means it may be installed in any PCIe slot from 1x to 16x. It is recommended that it is installed in the smallest slot in you computer, as it will not use the higher bandwidth available in 4x, 8x and 16x slots.
Open your computer.
Identify PCIe slot.
Insert and secure.
Close the computer.
Open your Control Panel from the Start menu. Double click on Administrative Tools. Double click on Computer Management and click on Device Manager in the left hand panel

If the old MSPorts driver is loaded, you will see each of the serial ports under 'Ports (COM & LPT)' but there will be no 'Mulitfunction adapters' leaf above the 'Ports (COM & LPT)' (see the next image for a correct example). If this is your current setup, please uninstall the MSPorts drivers using the uninstall procedure in troubleshooting below.
The correct drivers are load here, with enteries under the 'Ports (COM & LPT)' and the 'Mulitfunction adapters'.
There should be four entries in each, and the COM ports should be sequential 5, 6, 7, 8 for the default install

04040000 = Cable 1 (should be COM5)
04050000 = Cable 2 (should be COM6)
04060000 = Cable 3 (should be COM7)
04070000 = Cable 4 (should be COM8)
If this is not how your system is setup, please correct the assignments as outlined here.
fig. Scan for hardware changes to find the board
fig. Found new hardware, do not connect to windows update
fig. Found new hardware, communications port
fig. Use installed Drastic drivers, or CD Drastic drivers
fig. OXCB950 Cardbus UART installed (1 of 4)
fig. Found new hardware for 16c95x Serial Port
fig. 16c95x Serial Port
fig. Install 16c95x driver from Drastic install or CD
fig. PCI Communications Port installed
fig. Correct driver will have 4 Cardbus UARTS and 4 PCI Communication Ports
Restart the machine

To manually assign the com ports correctly, start by right clicking on a port and looking at its 'Details' page. Under Device Instance Id there will be a description in the form of OXPCIMF\*PNP05-1\040#0000. These numbers at the end describe the physical, or cable, port order. The IDs match the cable numbers in the following way:
04040000 = Cable 1 (should be COM5)
04050000 = Cable 2 (should be COM6)
04060000 = Cable 3 (should be COM7)
04070000 = Cable 4 (should be COM8)

Clicking on the Settings tab should display this dialog.

Clicking on the Advanced button on the Settings tab will bring up the COM Port Number selector. This is where you will set the com port per the table above. Do not worry if the port is marked 'Used'. Once all the ports are configured correctly there should be no conflicts.
fig. Select setup language
fig. Setup welcome screen
fig. Select installation path (please leave as default)
fig. Select Start menu group name (please leave as default)
fig. Installation summary
fig. Restart the machine
Once the machine has restarted, please run the Drastic 422 Config utility to setup the ports to their default position and state.
fig. Run Drastic 422 Config from Start menu
fig. Click the Set COM5..8 button
fig. Restart the machine
fig. Select the port to uninstall
fig. Confirm the un-installation
fig. Port now removed, repeat for other 3 ports
fig. All ports removed
The correct drivers can now be setup as specified above.